Inflammatory bowel disease incidence: up, down or unchanged?

Inflammatory bowel disease incidence: up, down or unchanged?

Inflammatory bowel disease or irritable bowel syndrome?

Gastrointestinal complaints are one of the most common reasons individuals seek medical care. Many have been through numerous physician consultations and treatment modalities without relief. Unfortunately, millions more suffer silently, thinking that their GI symptoms are “normal”; while self-medicating with antacids, Pepto Bismal or food avoidance. Additionally, many GI complaints are embarras...

Neonatal Presentation of Unremitting Inflammatory Bowel Disease

Very-early-onset inflammatory bowel disease (VEO-IBD) has a distinct phenotype and should be considered a specific entity. VEO-IBD presents with very severe clinical pictures and is frequently known by an indeterminate colitis whose clinical remission is unmanageable. This study examines the case of a neonate with VEO-IBD, not responding to medical and surgical treatment. A 7-day-old Iranian fe...

Recent trends in the epidemiology of inflammatory bowel diseases: up or down?

Inflammatory bowel disease (IBD) is traditionally considered to be common in the Western world, and its incidence has sharply increased since the early 1950s. In contrast, until the last decade, low prevalence and incidence rates have been reported from other parts of the world including Eastern Europe, South America, Asia and the Pacific region. Recent trends indicate a change in the epidemiol...

Evolving inflammatory bowel disease treatment paradigms: top-down versus step-up.

Crohn disease (CD) and ulcerative colitis (UC) comprise a group of inflammatory disorders of the gastrointestinal tract that can vary in severity of disease, anatomic extent of inflammation, presence and nature of extraintestinal manifestations, and response to therapeutic approaches. There have been attempts to classify CD based on the location and behavior of disease. Advances in understandin...